[Allergic Asthma Drugs]_Type_Classification

Jan 27, 2020 新闻

[Allergic Asthma Drugs]_Type_Classification

[Allergic Asthma Drugs]_Type_Classification

Asthma is actually a respiratory disease.
However, allergic asthma differs from other asthma in that allergic asthma patients only develop the disease when they are exposed to allergens, and generally do not have severe symptoms.
But for patients with allergic asthma, some asthma medicines are also needed.
So, what drugs can help allergic asthma patients relieve symptoms?
Bronchodilators, in addition to their main role in dilating the bronchus and controlling the acute symptoms of asthma.
1.β2 agonist: β2 agonist drugs are mainly divided into fast-acting β2 agonists and long-acting β2 agonists.
① Fast-acting β2 agonists: including salbutamol, terbutaline and fenoterol, etc., the action time is 4-6 hours.
② Long-acting β2 agonists (LABA): including salmeterol, formoterol, and procaterol.
Action time> 12 hours, especially suitable for nighttime asthma.
Beta2 agonists are the first-line drugs to relieve the symptoms of an acute attack.
The β2 agonist can be administered by inhalation, oral or intravenous injection. The inhalation method is preferred, which has a rapid effect, a high amount of drugs in the airway, and few systemic side effects.
Methods of inhalation include quantitative aerosol, dry powder inhalation and continuous nebulization.
Quantitative aerosols are the most commonly used.
However, the use of quantitative aerosols needs to be combined with the use of aerosol cans to ensure efficacy.
2.Theophylline oral aminophylline is usually dosed at 5 to 8 mg / kg per day, and theophylline is slowly released at 8 to 12 mg / kg per day.
Intravenous administration is mainly used in critically ill asthma.
The first injection dose is 4-6mg / kg and it should be injected slowly. The injection time should be greater than 15min. The intravenous drip maintenance amount is 0 per hour.
8 ~ 1.
0mg / kg, daily dosage generally does not exceed 750mg ~ 1000mg.
3.Anticholinergic drugs Inhalation of anticholinergic drugs, such as Ipratropinebromide, etc., combined with β2 agonist inhalation therapy can enhance and last the bronchodilator effect. It is mainly used in asthma patients whose β2 agonist alone cannot control symptomsIt is particularly suitable when combined with chronic obstructive pulmonary disease.
Can be inhaled with MDI or continuous nebulization, 3 to 4 times a day, 75 to 250 μg each inhalation.
It takes about 15 minutes and lasts for 6 to 8 hours.
There are few adverse reactions, and a few patients have bitter or dry mouth.